Numa época em que as transformações económicas, políticas e sociais têm vindo a criar à física (e às ciências em geral) um novo contexto de investigação, procuro dar conta do modo como estes novos desafios, que se estendem ao domínio filosófico e cultural, estão a ser encarados pelos cientistas. Num momento em que a "ciência de investigação" ("académica", "normal") sofre uma retracção face à expansão duma ciência "pós-normal", "pós-académica", e em que, ao lado da clivagem entre as "duas" culturas (científica (...) e humanística) uma "terceira", de face tecnológica se vai impondo, aponta-se o risco da concepção duma física "imune" à mudança cultural. /// I attempt to show how scientists are dealing with some new challenges coming from both the philosophical and the cultural domains, in the new context of research that is being created to physics (and indeed to sciences in general) by economical, political and social changes. Now that "research science" (" academic", "normal") becomes less important than a "post-normal", "postacademic" one, and in a time that besides the distinction between the "two" cultures (scientific and humanistic) a "third" one of technological nature is being generally accepted, the danger is shown of conceiving physics as "immune" to cultural change. (shrink)

RésuméĽauteur commence par un bref diagnostic des tendances les plus notoires de ľépistémologie contemporaine, qui trouve dans ľopérationnalisme fonctionnaliste une ≫reponse≪ au paradoxe?une connaissance construite par transformation de ľobjet et elle relève les indications ≫thérapeutiques≪ qui se trouvent déja dans ľépistémologie de Gonseth, selon lesquelles il sera possible de réintégrer ľidée?objectivité et de vérité dans la connaissance. En trois aspects: dans le domaine de la méthodologie épistémologique – elle montre que Gonseth s'est aperçu de la valeur propédeutique?une gnoséologie scientifique, comme (...) condition de base?un abord cohérent de ľépistémologie. Dans le champ de la gnoséologie, elle montre que la coloration empiriste que Piaget a regretée dans les schémas gonséthiens, selon lui trop ouverts à un contact actuel et extérieur avec ľobjet, fournit, après tout, une indication aujourdi'hui précieuse pour contrebalancer les exagérations opposées?une gnoséologie qui fait, de ľautoréférence et de la clôture du sujet, ľune des justifications de ľimpossibilité de fonder objectivement la connaissance. Finalement, elle considère que, dans le champ?une lecture philosophique des sciences, le relativisme dialectique de Gonseth récupere la valeur pragmatique et?objectivité≫circonscrite≪ de la connaissance, sans pour autant abandonner ľidée?une progression en objectivité.SummaryThe author begins with a consideration of well‐known trends of contemporary epistemology, which finds in functionalist operationalism a ‘response’ to the paradox of knowledge achieved by transformation of the object. The author goes on to note the ‘therapeutic’ indications already available in the epistemology of Gonseth, which make it possible to reintegrate the idea of objectivity and of truth into knowledge. This is done in three respects. In epistemological methodology, it is shown that Gonseth was aware of the preparatory value of a scientific gnoseology as the fundamental condition for a coherent approach to epistemology. In gnoseology, it is shown that the empirical aspect of Gonseth's schemes, which Piaget found regrettable as being too open to immediate and exterior contact with the object, does after all provide an indication that is invaluable in offsetting the opposing exaggerations of a gnoseology that makes the self‐reference and closedness of the subject one of the justifications for the impossibility of founding knowledge objectively. Finally, it is held that, on a philosophical reading of the sciences, the dialectical relativism of Gonseth recovers the pragmatic value and the value of ‘circumscribed’ objectivity of knowledge, without in so doing giving up the idea of an increase in objectivity. (shrink)

RésuméĽauteur commence par un bref diagnostic des tendances les plus notoires de ľépistémologie contemporaine, qui trouve dans ľopérationnalisme fonctionnaliste une ≫reponse≪ au paradoxe ?une connaissance construite par transformation de ľobjet et elle relève les indications ≫thérapeutiques≪ qui se trouvent déja dans ľépistémologie de Gonseth, selon lesquelles il sera possible de réintégrer ľidée ?objectivité et de vérité dans la connaissance. En trois aspects: dans le domaine de la méthodologie épistémologique – elle montre que Gonseth s'est aperçu de la valeur propédeutique ?une (...) gnoséologie scientifique, comme condition de base ?un abord cohérent de ľépistémologie . Dans le champ de la gnoséologie , elle montre que la coloration empiriste que Piaget a regretée dans les schémas gonséthiens, selon lui trop ouverts à un contact actuel et extérieur avec ľobjet, fournit, après tout, une indication aujourdi'hui précieuse pour contrebalancer les exagérations opposées ?une gnoséologie qui fait, de ľautoréférence et de la clôture du sujet, ľune des justifications de ľimpossibilité de fonder objectivement la connaissance. Finalement, elle considère que, dans le champ ?une lecture philosophique des sciences, le relativisme dialectique de Gonseth récupere la valeur pragmatique et ?objectivité≫circonscrite≪ de la connaissance, sans pour autant abandonner ľidée ?une progression en objectivité.SummaryThe author begins with a consideration of well‐known trends of contemporary epistemology, which finds in functionalist operationalism a ‘response’ to the paradox of knowledge achieved by transformation of the object . The author goes on to note the ‘therapeutic’ indications already available in the epistemology of Gonseth, which make it possible to reintegrate the idea of objectivity and of truth into knowledge. This is done in three respects. In epistemological methodology, it is shown that Gonseth was aware of the preparatory value of a scientific gnoseology as the fundamental condition for a coherent approach to epistemology . In gnoseology , it is shown that the empirical aspect of Gonseth's schemes, which Piaget found regrettable as being too open to immediate and exterior contact with the object, does after all provide an indication that is invaluable in offsetting the opposing exaggerations of a gnoseology that makes the self‐reference and closedness of the subject one of the justifications for the impossibility of founding knowledge objectively. Finally, it is held that, on a philosophical reading of the sciences, the dialectical relativism of Gonseth recovers the pragmatic value and the value of ‘circumscribed’ objectivity of knowledge, without in so doing giving up the idea of an increase in objectivity. (shrink)

O presente artigo pretende dar conta de alguns dos aspectos mais salientes da questão relativa à pertinência da Filosofia (especialmente na qualidade de Filosofia da Ciência) para a prática científica dos cientistas. Nesse sentido, a autora recorre sobretudo a exemplos vigentes nos finais do século xx, dando especial relevância a manifestações de "impaciência" por parte de alguns investigadores em relação a algumas críticas epistemológicas e éticas dos filósofos, sobretudo no que se refere à famosa controvérsia da "guerra das ciências" e (...) a toda uma ofensiva cultural relativa a uma terceira cultura que apresenta os cientistas como sendo os novos humanistas e em que os "filósofos empíricos" estariam a perder peso. Como resposta, a autora propõe que, embora possam ser dispensáveis no laboratório, aos filósofos deve ser reconhecida a capacidade de disponibilizar às ciências uma linguagem que seja capaz de facilitar o diálogo cultural alargado, uma linguagem, portanto, de que as próprias ciências não se poderão dispensar se realmente quiserem sobreviver no âmbito da cultura do século XXI. /// The present article intends to give an account of some of the more relevant aspects pertaining to the question about the importance of Philosophy, and in particular Philosophy of Science, for the scientific work of scientists. The author of the article gives special attention to examples taken from the scientific landscape at the end of the xx Century, whereby special consideration is given to the impatience shown by some scientists in relation to some epistemological and ethical criticisms coming from the side of Philosophy. Particular attention is given to the famous "war of sciences" and the cultural offensive related to the introduction of a third culture in which the scientists are presented as the new humanists and in which even the "empirical philosophers" were losing weight. In that sense, the author suggests that, even though they might be of not much use in the laboratory, the philosophers keep intact the capacity of offering to the sciences a language that is capable of facilitating the cultural dialogue at large, a language, therefore, of which the sciences will not be able to dispense themselves should they want to thrive and be culturally influential in the XXI century. (shrink)

Der alle drei Jahre tagende Kongress der „Deutschen Gesellschaft für Philosophie“ (DGPhil) ist der größte Kongress für Philosophie in Deutschland. Vom 11.-15. September fand er diesmal an der Ludwig-Maximilians-Universität in München statt. Mit rund 1600 Teilnehmern und über 400 philosophischen Vorträgen fiel er, auch durch den Veranstaltungsort bedingt, wesentlich umfangreicher aus als der XXI. Kongress in Essen.

Famous Brazilian educational and social theorist Paulo Freire presents his ideas on community solidarity in moving toward social justice in schools and society in a set of talks and interviews shortly before his death, supplemented with ...

O presente artigo propõe refletir sobre a vivência ético-política-afetiva na comunidade. Discute-se três pontos principais: 1. Como se dá a ética, a política e os afetos em uma comunidade a partir da Filosofia de Espinosa. 2. Partindo-se da compreensão da dinâmica dos afetos como se pode compreender a liberdade e a servidão na vivência comunitária. Como a comunidade age ou não de tal forma que a liberdade ou a servidão, respectivamente, passam a ser vivenciadas no ambiente comunitário? O que poderá (...) favorecer a liberdade ou a servidão? 3. Proposta de uma ação compartilhada dos profissionais. O objetivo dessa análise é revisitar a reflexão sobre ética, política e afetos na comunidade e, a partir de Baruch de Espinosa, proporcionar uma análise que reatualize o que seja comunidade na perspectiva essa revisitação. O conceito de comunidade que esse artigo se refere diz respeito ao conjunto de pessoas que convivem no mesmo território ou no mesmo bairro e que, no quotidiano, vivenciam diversas experiências. Tem-se como reflexões principais que, mediante a compreensão da dinâmica instável dos afetos, os profissionais que ‘atuam’ em comunidades, poderão ter uma visão mais ampla sobre suas práticas e se as mesmas fomentam ou aumentam estados de servidão ou se, ao contrário, contribuem para a liberdade da comunidade e dos indivíduos. (shrink)

Por incorporar a esperança na pedagogia crítica para, um só tempo, humanizar radicalmente a educação e transformar a sociedade, ele faz aumentar nossas expectativas sobre o que são capazes de fazer uma teoria e uma pedagogia ao construir um caminho que demonstra a indissociabilidade de ordem teórica e prática.

The company at the service of today's society is reinventing itself to satisfy people's needs in a more efficient and adapted way. Globalization and digitization promote increasing interaction and new forms of economic organization such as collaborative economy. However, can it be understood that this new business model, more than others, has as its raison d'être in the search for the “common good”? A first approach suggests the presence of values related to collaboration between equals aiming at a common good. (...) However, the possible existence of a profit motive and the labor relations framework in which certain activities are carried out have created a debate on their ethical qualification. In this context, considering 278 companies in the collaborative economy sector, the relationship between the concept of “common good” and the collaborative economy is analyzed, while examining whether these new realities have an explicit ethical intention (of search for goods for people). According to the results, it is not possible to assert that these platforms have an ethical concern, but it is observed that they are in line with the common good and implicitly contribute to the service of society. (shrink)

The present study aims to verify the psychometric properties of the Spanish versions of the Social Roles Questionnaire (SRQ; Baber & Tucker, 2006), Modern Sexism scale (MS) and Old-fashioned Sexism scale (OFS; Swim et al. Swim & Cohen, 1997). Enough support was found to maintain the original factor structure of all instruments in their Spanish version. Differences between men and women in the scores are commented on, mainly because certain sexist attitudes have been overcome with greater success in the current (...) Spanish society, while other issues, such as distribution of power in organizational hierarchies or distribution of tasks in the household, where traditional unequal positions are still maintained. In all cases, it was found that men showed greater support for sexist attitudes. The correlations between the three instruments were as expected in assessing sexist attitudes that tend to relate to each other. Eventually, we found no empirical evidence for the postulated link between sexist attitudes and traditional gender stereotypes. Our results call for the validity and effectiveness of the classic theories of gender psychology, such as gender schema theories (Well, 1981; Markus et al., 1982) and the notion of a gender belief system (Deaux & Kite, 1987; 2001). (shrink)

The number of available legal documents has presented an enormous growth in recent years, and the digital processing of such materials is prompting the necessity of systems that support the automatic relevant information extraction. This work presents a system for ontology-based information extraction from natural language texts, able to identify a set of legal events. The system is based on an innovative methodology based on domain ontology of legal events and a set of linguistic rules, integrated through inference mechanism, resulting (...) in a flexible approach and scalable approach. A case study with the use of documents from the Superior Court in Brazil is related, with satisfactory results in precision and recall. (shrink)

Introduction: In 2020, according to the Global Cancer Observatory, nearly 10 million people died of cancer. Amongst all cancers, breast cancer had the highest number of new cases and lung cancer had the highest number of deaths. Even though the literatures suggest a possible connection between psychological factors and cancer risk, their association throughout studies remains inconclusive. The present systematic review studied the connection between psychological factors and the risk of breast and lung cancer, prior to a cancer diagnosis. The (...) psychological factors of trauma, grief, and depression were studied.Methods: The current systematic review was carried out across multiple databases in two phases, an initial exploratory research in June 2020, refined with a second electronic research in December 2020. The inclusion criteria included studies describing the association between trauma, posttraumatic stress disorder, grief, and depression with breast and lung cancer risk. The psychological data collection must have been carried out prior to a confirmed breast or lung cancer diagnosis, and accessed through self-report measures, questionnaires, clinical interviews, or clinical diagnoses. Study reports had to contain information about the incidence of cancer and effect size. The exclusion criteria were studies in which psychological factors were collected after cancer diagnosis.Results and Conclusion: A total of 26 studies were included. Although non-consensual, the findings from the present systematic review suggest that, in addition to the known risk factors, psychological factors may play an important role in the etiology of both breast and lung cancer. To include psychological factors as a variable that affects cancer development may be fundamental to opening new avenues for prevention and intervention.Systematic Review Registration: [www.ClinicalTrials.gov], identifier [CRD42020209161]. (shrink)

Este artigo propõe uma discussão sobre jornalismo e subjetividade a partir de uma argumentação que considera que, embora o discurso hegemônico sobre a instituição se construa a partir do ideal da objetividade, de um texto constituído apenas pelos fatos e cujo autor deixa de ser sujeito para assumir a identidade de jornalista, a subjetividade foi sempre constituidora do texto jornalístico. Assim, pensando a partir dos estudos culturais o jornalismo como uma instituição social com formas, valores e funções conformados historicamente, e (...) os sujeitos como indivíduos que se reconhecem a partir de uma ampla rede de relações de poder, de tradições culturais, de representações de identidades, argumentamos que, em um contexto cada vez maior de centralidade dos sujeitos na cultura contemporânea, os discursos sobre si tem sido uma forte tendência também no jornalismo. (shrink)

Pretendemos mostrar que, no Górgias, diálogo dedicado à crítica da retórica, as frequentes alusões de Sócrates à compleição do corpo, bem como o uso recorrente de metáforas corpóreas para referir-se ao que, por analogia, passa-se com a alma servem de ferramenta retórica para fazer frente à retórica de Górgias. Desse modo, ao mesmo tempo em que chamamos atenção para a maneira como Platão se vale das armas do adversário justamente para atacá-lo, ressaltamos o papel imprescindível do corpo como evidência da (...) alma na filosofia platônica. Com isto, nosso intuito é reforçar a vertente interpretativa segundo a qual Platão pode ser entendido mais como um pensador que parte dos problemas prementes de seu tempo para daí nos conduzir a reflexões filosóficas – no diálogo em questão, as consequências políticas de uma paidéia pautada numa retórica sofística –, do que como um filósofo comprometido apenas com uma metafísica transcendente. (shrink)

We intend to point out that in the Gorgias, dialogue devoted to the critique of rhetoric, Socrates' frequent allusions to the body's complexion, and the recurrent use of corporeal metaphors to refer to what, by analogy, happens to the soul, function as a rhetoric tool in order to oppose Gorgias' own rhetoric. Thus, while drawing attention to the way Plato uses the weapons of the adversary precisely to attack him, we emphasize the indispensable role of the body as evidence of (...) the soul in Platonic philosophy. Therefore, our intent is to reinforce the interpretive strand according to which Plato can be understood more as a thinker who departs from the pressing problems of his time in order to lead us into philosophical reflections – in the present dialogue, the political consequences of a _paideia _oriented by sophistic rhetoric –, than as a philosopher solely committed to a transcendent metaphysics. (shrink)

Implementing corporate social responsibility (CSR) in supply chains is not a trivial task. In fact, many firms in recent years have publicly proclaimed that in order to keep their CSR commitments, they had to reduce reliance on external suppliers by vertically integrating their operations. Our aim in this article is to examine whether there is truly a relationship between a firm’s CSR performance and its level of vertical integration. Drawing on a multi-industry sample of 2,715 firm-year observations, and after addressing (...) endogeneity concerns, we demonstrate that firms with higher CSR performance tend to vertically integrate more (or, outsource less). We also demonstrate that this tendency is weaker for firms that have higher degrees of asset specificity or international diversification. Our core conclusion is that CSR performance and outsourcing are at odds, but firms can reconcile this tension by deepening their collaborations with suppliers. (shrink)

We show that g ≤ c(Sym(ω)) where g is the groupwise density number and c(Sym(ω)) is the cofinality of the infinite symmetric group. This solves (the second half of) a problem addressed by Thomas.

A PORTABILIDADE DOS PLANOS DE ASSISTÊNCIA PRIVADA À SAÚDE: UMA ANÁLISE SOB A PERSPECTIVA CONSUMERISTA.

Ante ciertos modelos causales del agente libre inspirados en Tomás de Aquino, resulta interesante atender al modelo causal presentado por Tomás mismo, especialmente en un texto a partir del cual se puede rastrear la exposición de la acción libre como el efecto de los cuatro sentidos causales aristotélicos. Se trata de la cuestión sobre los actos imperados (ST I–II, q. 17); en cuyos primeros cuatro artículos –y en sus textos paralelos– determina que la voluntad es causa agente; la razón práctica, (...) causa ordenadora; y el imperium de ambas (razón y voluntad) se relaciona con el acto imperado como lo formal con lo material. (shrink)

Este artigo, de caráter teórico, apresenta uma discussão sobre as redes sociais. Para isto, comenta diversos organismos de pesquisa, publicação e divulgação sobre a temática, assim como faz uma apanhado geral de revistas e livros dedicados a explicação e conceitualização destas. Depois de apresentad..

Este repertorio registra información de Husserl en la Internet, una breve historia sobre los Nachlaß, el índice de la Husserliana, un listado de las publicaciones de y sobre Husserl disponibles en la Biblioteca Central de la Pontificia Universidad Católica del Perú, y los artículos sobre Husserl que se encuentran en la Hemeroteca. El listado abarca las publicaciones existentes hasta el año 1997.

ENTREVISTA COM PROFISSIONAIS DA FILOSOFIA QUE ATUAM EM PROJETOS – BLOCO ICom: Lucas Dilacerda, Paulo Jorge Leandro, Paulo W. Lima, Raquel R. RochaPor: Antônio Alex Pereira de Sousa, Paulo Willame Araújo de Lima.

1a pt. Socrática. t. 1. Cármides ; Lisis ; Eutifron ; Apología; Critón ; Fedón ; Menón -- t. 5. Eutidemo ; Gorgias -- t. 7-8. República.

This article reflects on childhood times based on the words chrónos, kairós and aión, which the Greeks use to conceptualize time, in dialogue with different authors, such as Kohan, Pohlmann, Skliar, Kohan and Fernandes. In the pedagogical field, we explore how Pedagogy of Childhood has focused on the importance of childhood temporality and children’s agency, with contributions from Hoyuelos, Parrini, Aguilera et al., Barbosa, Oliveira-Formosinho e Araújo, Oliveira-Formosinho, Pinazza and Gobbi. We reflect on what forms of organizing time are possible (...) when we think about children and their childhoods. Would it be a continuous and chronological time, a time of opportunity for the instant or the timeless intensity of the aiónic? Would it be possible to open spaces in school for other temporalities, given its immersion in chronological time, and its extreme emphasis on routine? We seek a relationship between forms of temporality, philosophy, and early education in order to explore alternative possibilities in the relationship between child and the school context, and conclude that, since the child’s is the aiónic time of intense experience, it is in the heightened dynamic immediacy and the multiple symbolic languages of play that it may be possible to create pedagogical structures that provide a dwelling for childhood temporality. (shrink)

Sensor-based data are becoming increasingly widespread in social, behavioral and organizational sciences. Far from providing a neutral window on 'reality', sensor-based big-data are highly complex, constructed data sources. Nevertheless, a more systematic approach to the validation of sensors as a method of data collection is lacking, as their use and conceptualization have been spread out across different strands of social-, behavioral- and computer science literature. Further debunking the myth of raw data, the present article argues that, in order to validate (...) sensor-based data, researchers need to take into account the mutual interdependence between types of sensors available on the market, the conceptual (construct) choices made in the research process, and the contextual cues. Sensor-based data in research are usually combined with additional quantitative and qualitative data sources. However, the incompatibility between the highly granular nature of sensor data and the static, a-temporal character of traditional quantitative and qualitative data has not been sufficiently emphasized as a key limiting factor of sensor-based research. It is likely that the failure to consider the basic quality criteria of social science measurement indicators more explicitly may lead to the production of insignificant results, despite the availability of high volume and high-resolution data. The paper concludes with recommendations for designing and conducting mixed methods studies using sensors. (shrink)

Neste artigo, depois de nos referirmos brevemente à exterioridade e ao carácter estrangeirado do Positivismo Português, pretendemos mostrar que Antero de Quental, no seu eclectismo e sem contradição, é positivista no plano da ciência—sem, no entanto, se pronunciar claramente sobre as específicas teses do positivismo—apesar de ser antipositivista no plano da filosofia onde se apresenta como acérrimo defensor da metafísica. Ao longo da sua obra é clara a sua admiração pela ciência positiva e evidente a sua defesa da ciência contra (...) a religião. /// After a brief mention of the imported character of Portuguese Positivism, we aim to show that, in his eclecticism, Antero de Quental is a positivist in science-although he never clearly criticized the specific thesis of positivism-while at the same time he was antipositivist in philosophy, strongly supporting metaphysics. Throughout his work both his appreciation of positivistic science and his defense of science against religion remain clear. (shrink)

The company at the service of today's society is reinventing itself to satisfy people's needs in a more efficient and adapted way. Globalization and digitization promote increasing interaction and new forms of economic organization such as collaborative economy. However, can it be understood that this new business model, more than others, has as its raison d'être in the search for the “common good”? A first approach suggests the presence of values related to collaboration between equals aiming at a common good. (...) However, the possible existence of a profit motive and the labor relations framework in which certain activities are carried out have created a debate on their ethical qualification. In this context, considering 278 companies in the collaborative economy sector, the relationship between the concept of “common good” and the collaborative economy is analyzed, while examining whether these new realities have an explicit ethical intention (of search for goods for people). According to the results, it is not possible to assert that these platforms have an ethical concern, but it is observed that they are in line with the common good and implicitly contribute to the service of society. (shrink)

O trabalho discute os fundamentos da educação e as contribuições da filosofia para a educação e para a pedagogia. A análise, em andamento, constitui nossas pesquisas na universidade, investigando as concepções pedagógicas e os pressupostos e fundamentos da educação. O texto de caráter teórico-bibliográfico apresenta uma síntese nas correntes da filosofia da educação, identifica a função social, os limites e as possibilidades desse complexo considerando a especificidade da sociedade de classes. Dessa forma, apoia-se em Saviani (2012, 2013, 2013a), Aranha (1996) (...) e Severino (1995). A educação e a formação humana no modo de produção capitalista perpassam por mecanismos explícitos e implícitos inerentes às teorias educacionais e à práxis educativa determinando as concepções de homem, de mundo e de sociedade. (shrink)

Bullying is a phenomenon that affects children and adolescents worldwide, and it has major consequences for all participants involved in these situations. In Chile, researchers have validated several instruments used to investigate aggression between peers and school violence, but there is a lack of validation of instruments to investigate bullying. The purpose of this study was to provide evidence of the validity and reliability of the Olweus Bully/Victim Questionnaire—Revised version in the Chilean context. The participants were 2,775 students from schools (...) of low, medium, and high socioeconomic status. OBVQ-R is a self-report questionnaire with 42 items, which has been used in different countries, and has adequate psychometric properties to assess the prevalence of victimization and aggression and various forms of bullying worldwide. Results confirmed the two-factor structure of the OBVQ-R and good reliability. These dimensions seem to be correlated. Comparison between OBVQ-R with the School Violence between Peers Questionnaire and the Internet Experiences Questionnaire showed some degree of agreement. The Item Response Theory analysis showed that the item about verbal bullying, in both subscales, had the lowest-severity parameters, meaning that these forms of bullying were the most prevalent. The higher-severity parameter in the victimization scale was the cyberbullying item, and the sexual bullying item showed higher severity in the perpetration subscale. The differential item functioning analysis by gender showed a trend in which boys responded with lower-severity parameters than girls. In the victimization scale, the exception was the item about spreading rumors, and in the perpetration subscale, it was the item about racial bullying. We have provided evidence of the validation of OBVQ-R among school-age children and adolescents in Chile. This study is part of a trial registered at ClinicalTrials.gov, number NCT02898324. (shrink)

The topology of DNA duplexes changes during replication and also after deproteinization in vitro. Here we describe these changes and then discuss for the first time how the distribution of superhelical stress affects the DNA topology of replication intermediates, taking into account the progression of replication forks. The high processivity of Topo IV to relax the left‐handed (+) supercoiling that transiently accumulates ahead of the forks is not essential, since DNA gyrase and swiveling of the forks cooperate with Topo IV (...) to accomplish this task in vivo. We conclude that despite Topo IV has a lower processivity to unlink the right‐handed (+) crossings of pre‐catenanes and fully replicated catenanes, this is indeed its main role in vivo. This would explain why in the absence of Topo IV replication goes‐on, but fully replicated sister duplexes remain heavily catenated. (shrink)